Warfarin or Coumadin is a compound or drug that acts indirectly as an anticoagulant (it has no direct anticoagulant effect) by interfering with the action of vitamin K1 in the synthesis of the coagulation factors II, VII, IX, and X. It is often used in animals and people to help patients that are throwing blood clots.
I realize the accompanying photos are pretty gross, but I wanted to make an important point here! I'm 40 minutes from town and 2 & 1/2 hours from my practice here at the cabin...what can I do to make my pets vomit to decontaminate them? I reached under the bathroom sink for my brown bottle of hydrogen peroxide (H2O2). In my practice, we use a drug which is an opioid (morphine-like drug) called Apomorphine that can be given IV, SQ or in the conjunctival sac of the eye. I was taught in veterinary school, by a world class toxicologist, that H2O2 is a safe and effective way to induce emesis or vomiting in our dogs. I use a dosage of 0.5-1 ml/lb, no more than 45 ml total volume, and no more than two times dosing with it. The antidote or treatment after emesis is induced is to treat them with vitamin K1.
A side note: I don't use Peroxide for anything else except to clean blood off of hair after surgery. Peroxide is commonly used to clean healing wounds which is a bad idea because it causes free radical damage to the healing tissue...which is obviously counter productive!
The Guilty Party!

9 comments:
Shawn,
I'm glad your dogs are okay.
Andy
Shawn,
You have some amazing knowledge! If that happened to my dog I would have just called you. Hopefully I never have to.
Eric
Hope everyone is fine.
Lizzie and I wrote down your instructions in case of emergency. Thanks
Shawn,
Where do you put the H202? In the eye sac?
Andy
Andy...
You make them swallow the peroxide! The Apomorphine goes in the conjunctival sac of the eye...but, in my hands that mode doesn't work that well!
Shawn: will write this one down, too, and throw a bottle of peroxide into the big travelling first-aid kit, too.
Good reminder about why not to use peroxide for wound-care, too.
best
Andrew
After inducing the vomiting, did you also go ahead and treat with vitamin K?
Jim...
I did not treat with Vit K1 due to the fact that I got all the stuff back! I typically treat my clients' dogs with it though to cover my butt!
Thanks for the info and the great post. I'm glad your dogs were ok.
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